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M.TaoJ.ReidyK.et al (2016)

Since crystallins are long-lived stable proteins with minimal turnover, accumulation of oxidative damage leads to protein cross-linking, aggregation, insolubility, and fragmentation, resulting in the formation of cataracts

A well-known complement resistance mechanism that acts at the C4 step is the use of the host protein Factor I with cofactors, such as C4 binding protein (C4BP) 2,37,38

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But cancer becomes very interesting because there was a study in rodents that showed that stretching prevents tumor growth